1 edition of Metabolism and biological functions of polyamines. found in the catalog.
Metabolism and biological functions of polyamines.
|Series||Annals of the New York Academy of Sciences -- v. 171, art. 3|
|Contributions||Herbst, Edward J., Bachrach, Uriel.|
|The Physical Object|
|Pagination||693-1009 p. illus. ;|
|Number of Pages||1009|
Plant Specialized Metabolism: Genomics, Biochemistry, and Biological Functions will provide the reader with special insights into the sophisticated nature of these metabolites and their various and valuable uses based on the most recent findings in science. The field of plant specialized metabolism has witnessed tremendous growth in the past Cited by: 7. Polyamines (PAs) putrescine+2 (Put), spermidine+3 (Spd), spermine+4 (Spm), and cadaverine+2 (Cad) are low-molecu-lar-weight organic polycations displaying a high biological activity. PAs are present in all compartments of the plant cell, including the nucleus, which indicates their participa-tion in diverse fundamental processes in the cell.
It was not until recent years that the study of polyamines, their mechanisms of synthesis, and the roles they play in metabolism have flourished, becoming a fertile field of intense research. Polyamines in Fungi: Their Distribution, Metabolism, and Role in Cell Differentiation and Morphogenesis provides a complete overview of its topic. It is the fCited by: 4. Polyamines are also present as a conjugated form with cinnamic acids and proteins and the genes responsible for these conjugations have been increasingly identified. This Special Issue of Plants will highlight new discoveries about the metabolism and function of plant polyamines and help to stimulate further research. I also hope that it will.
Metabolism refers to any chemical process occurring within or between cells. There are two types of metabolism: Anabolism, where smaller molecules are synthesized to make larger ones; and catabolism, where larger molecules are broken down into smaller ones. . Biological function Although it is known that the biosynthesis of polyamines is highly regulated, the biological function of polyamines is only partly elucidated. In their cationic ammonium form, they bind to DNA, and, in structure, they represent compounds with cations that are found at regularly spaced intervals (in contrast to Mg 2+.
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Get this from a library. Metabolism and biological functions of polyamines. Editors: Edward J. Herbst and Uriel Bachrach. [Uriel Bachrach; Edward J Herbst;] -- Papers of a conference held by the Academy on April 9 Metabolism of Polyamines Biosynthesis The biosynthetic pathway for polyamines in Metabolism and biological functions of polyamines.
book is shown in Fig 1. The primary precursors of polyamines in both microorganisms and animal tissues are L- arginine and L-methionine. Ornithine, which is formed by the action of arginase (ECCited by: 6. Polyamines in Fungi: Their Distribution, Metabolism, and Role in Cell Differentiation and Morphogenesis provides a complete overview of its topic.
It is the first and only book to describe and analyze the roles of polyamines in fungi and compare them with the roles of polyamines in higher eukaryotes. Identification, Chemical Synthesis, and Biological Functions of Unusual Polyamines Produced by Extreme Thermophiles Tairo Oshima, Toshiyuki Moriya, and Yusuke Terui6.
Polyamine Block of Inwardly-Rectifying Potassium Channels Harley T. Kurata, Wayland W.L. Cheng, and Colin G. NicholsPart III: Transgenic Models for Study of Polyamine : $ Polyamines are ubiquitous small basic molecules that play multiple essential roles in mammalian physiology.
Their cellular content is highly regulated and there is convincing evidence that altered metabolism is involvement in many disease states. Drugs altering polyamine levels may therefore have a variety of important by: In Polyamines: Methods and Protocols, leading researchers contribute an extensive collection of up-to-date laboratory techniques for the further pursuit of polyamine study.
The volume delves into vital subjects such as neoplasia studies with animal models and human patients, therapeutic roles for polyamine inhibitors and analogs, polyamine. Polyamine Content and Metabolism. The polyamines synthesized by mammals are the triamine spermidine, the tetramine spermine, and their precursor putrescine.
Traces from dietary sources of other polyamines such as agmatine may be present in human tissues, but there is no convincing evidence that these play any physiological by: Comprehensive and cutting-edge, Polyamines: Methods and Protocols provides a key resource for all scientists pursuing the study of this dynamic and significant aspect of cellular biology.\/span>\"@ en\/a> ; \u00A0\u00A0\u00A0\n schema:description\/a> \" Current status of the polyamine research field \/ Anthony E.
Pegg and Robert A. Casere, Jr. The role of polyamines in the cell cycle, cell division, tissue growth, and differentiation is considered. Recent studies using highly specific inhibitors of polyamine biosynthesis such as alpha-difluoromethylornithine to prevent accumulation of polyamines have indicated that the synthesis of polyamines is intimately associated with these Cited by: Polyamines are low molecular weight aliphatic polycations, highly charged and ubiquitously present in all living cells.
Interest has been increasing during the last 30 years in the naturally abundant polyamines putrescine (diamine), spermidine (triamine) and spermine (tetramine), which were demonstrated to be involved in a large number of cellular processes.
Since polyamines are protonated at normal cellular pH, their biological function was initially associated with the capability of binding diVerent anionic macromolecules (DNA, RNA, chromatin and proteins), thus conWning them as substances with a structural role. However, it was later conWrmed that in addition to stabilizing macromolecular.
Click on the title to browse this issue. 3 Inhibition of Enzymes Oxidizing Polyamines I. Introduction II. Copper Amine Oxidases III. Flavin-Dependent Enzymes in Polyamine Catabolism IV. Biological Consequences of Polyamine Oxidase Inactivation V. Conclusions References 4 Molecular and Cellular Functions of the Polyamines I.
Introduction II. Nucleic Acid Structure III. Macromolecular Book Edition: 1. Polyamines, the aliphatic nitrogenous bases of low molecular weight, play a significant role in the biosynthesis and function of nucleic acids in biological systems (Galston and Kaur Sawhney, ).
Polyamines, such as putriscine, spermidine, spermine, and cadavarine occur widely in. Polyamines are aliphatic cations present in all cells. In normal cells, polyamine levels are intricately controlled by biosynthetic and catabolic enzymes. The biosynthetic enzymes are ornithine decarboxylase, S‐adenosylmethionine decarboxylase, spermidine synthase, and spermine by: Advances in our understanding of the metabolism and molecular functions of polyamines and their alterations in cancer have led to resurgence in the interest of targeting polyamine metabolism as an Cited by: Abstract.
Unusual long polyamines such as caldopentamine and caldohexamine, and branched polyamines such as tetrakis(3-aminopropyl)ammonium and N 4-aminopropylspermidine were often found in cells of extreme thermophiles and hyperthermophiles belonging to both Bacteria and Archaea of these unusual polyamines are essential for life at extreme by: Request PDF | Polyamines in Fungi: Their Distribution, Metabolism, and Role in Cell Differentiation and Morphogenesis | Fungi are among the simplest eukaryotic organisms that are amenable to the.
Polyamines (PAs) are low molecular weight aliphatic nitrogenous bases containing two or more amino groups. They are produced by organisms during metabolism and.
Polyamines (PAs) are low molecular weight aliphatic nitrogenous bases containing two or more amino groups. They are produced by organisms during metabolism and are present in almost all cells. Because they play important roles in diverse plant growth and developmental processes and in environmental stress responses, they are considered as a new kind of plant by:.
Polyamines are organic cations found in all eukaryotic cells and intimately involved in, and required for, distinct biological functions.
An increasing body of evidence indicates that the regulation of cellular polyamines is a central convergence point for the multiple signaling pathways driving various cellular functions. It seems that apoplastic metabolism of polyamines of the host and the accumulation of H2O2 as a result of polyamine catabolism play important signalling role in plant-pathogen interactions.
The manipulation of the members of the polyamine-induced signalling pathways could increase the host plant resistance to biotic by: 5.Polyamine metabolism and function PEGG, ANTHONY E., AND PETER P.
MCCANN. PoZyamine metabohsm and function. Am. J. Physiol. (Cell Physiol. 12): CC, Polyamines are ubiquitous organic cations of low molecular weight. The content of these amines is closely regulated by the cell according to theCited by: